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Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetes

BACKGROUND: Diabetes promotes maladaptive changes in the endothelium that lead to its dysfunction and contribute to the vascular pathology of diabetes. We have previously reported the up-regulation of galectin-3, a β-galactoside-binding lectin, in the endothelium and sera of diabetic mice, implicati...

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Detalles Bibliográficos
Autores principales: Darrow, April L., Shohet, Ralph V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499178/
https://www.ncbi.nlm.nih.gov/pubmed/26047815
http://dx.doi.org/10.1186/s12933-015-0230-3