Cell-Permeant and Photocleavable Chemical Inducer of Dimerization**

Chemical inducers of dimerization (CIDs) have been developed to orchestrate protein dimerization and translocation. Here we present a novel photocleavable HaloTag- and SNAP-tag-reactive CID (MeNV-HaXS) with excellent selectivity and intracellular reactivity. Excitation at 360 nm cleaves the methyl-6...

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Detalles Bibliográficos
Autores principales: Zimmermann, Mirjam, Cal, Ruben, Janett, Elia, Hoffmann, Viktor, Bochet, Christian G, Constable, Edwin, Beaufils, Florent, Wymann, Matthias P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499241/
https://www.ncbi.nlm.nih.gov/pubmed/24677313
http://dx.doi.org/10.1002/anie.201310969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499241/
https://www.ncbi.nlm.nih.gov/pubmed/24677313
http://dx.doi.org/10.1002/anie.201310969

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