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Cell-Permeant and Photocleavable Chemical Inducer of Dimerization**
Chemical inducers of dimerization (CIDs) have been developed to orchestrate protein dimerization and translocation. Here we present a novel photocleavable HaloTag- and SNAP-tag-reactive CID (MeNV-HaXS) with excellent selectivity and intracellular reactivity. Excitation at 360 nm cleaves the methyl-6...
Autores principales: | Zimmermann, Mirjam, Cal, Ruben, Janett, Elia, Hoffmann, Viktor, Bochet, Christian G, Constable, Edwin, Beaufils, Florent, Wymann, Matthias P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499241/ https://www.ncbi.nlm.nih.gov/pubmed/24677313 http://dx.doi.org/10.1002/anie.201310969 |
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