Selective Targeting of Tumor and Stromal Cells By a Nanocarrier System Displaying Lipidated Cathepsin B Inhibitor**

Cathepsin B (CtsB) is a lysosomal cysteine proteinase that is specifically translocated to the extracellular milieu during cancer progression. The development of a lipidated CtsB inhibitor incorporated into the envelope of a liposomal nanocarrier (LNC-NS-629) is described. Ex vivo and in vivo studie...

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Detalles Bibliográficos
Autores principales: Mikhaylov, G, Klimpel, D, Schaschke, N, Mikac, U, Vizovisek, M, Fonovic, M, Turk, V, Turk, Boris, Vasiljeva, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499245/
https://www.ncbi.nlm.nih.gov/pubmed/24975267
http://dx.doi.org/10.1002/anie.201402305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499245/
https://www.ncbi.nlm.nih.gov/pubmed/24975267
http://dx.doi.org/10.1002/anie.201402305

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