A 3,4-trans-Fused Cyclic Protecting Group Facilitates α-Selective Catalytic Synthesis of 2-Deoxyglycosides**

A practical approach has been developed to convert glucals and rhamnals into disaccharides or glycoconjugates with high α-selectivity and yields (77–97 %) using a trans-fused cyclic 3,4-O-disiloxane protecting group and TsOH⋅H(2)O (1 mol %) as a catalyst. Control of the anomeric selectivity arises f...

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Detalles Bibliográficos
Autores principales: Balmond, Edward I, Benito-Alifonso, David, Coe, Diane M, Alder, Roger W, McGarrigle, Eoghan M, Galan, M Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499252/
https://www.ncbi.nlm.nih.gov/pubmed/24953049
http://dx.doi.org/10.1002/anie.201403543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499252/
https://www.ncbi.nlm.nih.gov/pubmed/24953049
http://dx.doi.org/10.1002/anie.201403543

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