A Simple and Sensitive HPLC Method for Fluorescence Quantitation of Doxorubicin in Micro-volume Plasma: Applications to Pharmacokinetic Studies in Rats

A validated HPLC method was developed to determine the doxorubicin concentration in a small volume of rat plasma (60 µL) with convenient fluorescence detection. Sample preparation includes a simple one-step liquid-liquid extraction using a minimum amount of organic solvent, with extraction recovery...

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Detalles Bibliográficos
Autores principales: Daeihamed, Marjan, Haeri, Azadeh, Dadashzadeh, Simin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499424/
https://www.ncbi.nlm.nih.gov/pubmed/26185503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499424/
https://www.ncbi.nlm.nih.gov/pubmed/26185503

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