Cargando…

A Simple and Sensitive HPLC Method for Fluorescence Quantitation of Doxorubicin in Micro-volume Plasma: Applications to Pharmacokinetic Studies in Rats

A validated HPLC method was developed to determine the doxorubicin concentration in a small volume of rat plasma (60 µL) with convenient fluorescence detection. Sample preparation includes a simple one-step liquid-liquid extraction using a minimum amount of organic solvent, with extraction recovery...

Descripción completa

Detalles Bibliográficos
Autores principales:	Daeihamed, Marjan, Haeri, Azadeh, Dadashzadeh, Simin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499424/ https://www.ncbi.nlm.nih.gov/pubmed/26185503

Ejemplares similares

Preparation, In-Vitro Characterization and Pharmacokinetic Evaluation of Brij Decorated Doxorubicin Liposomes as a Potential Nanocarrier for Cancer Therapy
por: Fazel, Mohammadtaghi, et al.
Publicado: (2018)

Preparation and Characterization of Stable Nanoliposomal Formulation of Fluoxetine as a Potential Adjuvant Therapy for Drug-Resistant Tumors
por: Haeri, Azadeh, et al.
Publicado: (2014)

Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge
por: Arzani, Gelareh, et al.
Publicado: (2015)

Doxorubicin-Loaded Multivesicular Liposomes (DepoFoam) as a Sustained Release Carrier Intended for Locoregional Delivery in Cancer Treatment: Development, Characterization, and Cytotoxicity Evaluation
por: Mahjoub, Mohammad Ali, et al.
Publicado: (2023)

State of the Art of Stimuli-Responsive Liposomes for Cancer Therapy
por: Heidarli, Elmira, et al.
Publicado: (2017)

Metabolite Parameters as an Appropriate Alternative Approach for Assessment of Bioequivalence of Two Verapamil Formulations
por: Haeri, Azadeh, et al.
Publicado: (2014)

An Investigation into the Role of P-Glycoprotein in the Intestinal Absorption of Repaglinide: Assessed by Everted Gut Sac and Caco-2 Cell Line
por: Yaghoobian, Morteza, et al.
Publicado: (2019)

Effect of Surfactant Type, Cholesterol Content and Various Downsizing Methods on the Particle Size of Niosomes
por: Nowroozi, Fatemeh, et al.
Publicado: (2018)

The Impact of Surfactant Composition and Surface Charge of Niosomes on the Oral Absorption of Repaglinide as a BCS II Model Drug
por: Yaghoobian, Morteza, et al.
Publicado: (2020)

Simultaneous determination of doxorubicin and its dipeptide prodrug in mice plasma by HPLC with fluorescence detection()
por: Han, Jing, et al.
Publicado: (2016)

Dorzolamide Loaded Niosomal Vesicles: Comparison of Passive and Remote Loading Methods
por: Hashemi Dehaghi, Mohadeseh, et al.
Publicado: (2017)

A Simple and Sensitive HPLC-MS/MS Assay for the Quantitation of Blonanserin and N-Desethyl Blonanserin in Rat Plasma and Its Application to Pharmacokinetic Study
por: Huang, Shan-qing, et al.
Publicado: (2022)

Simple and rapid validated HPLC-fluorescence determination of perampanel in the plasma of patients with epilepsy
por: Mohamed, Susan, et al.
Publicado: (2017)

Particle Size Tailoring of Quercetin Nanosuspensions by Wet Media Milling Technique: A Study on Processing and Formulation Parameters
por: Cheshmehnoor, Pegah, et al.
Publicado: (2023)

A Simple HPLC Method for the Quantitative Determination of Silybin in Rat Plasma: Application to a Comparative Pharmacokinetic Study on Commercial Silymarin Products
por: Ha, Eun-Sol, et al.
Publicado: (2019)

Sensitive and Rapid HPLC Method for Determination of Memantine in Human Plasma Using OPA Derivatization and Fluorescence Detection: Application to Pharmacokinetic Studies
por: Zarghi, Afshin, et al.
Publicado: (2010)

Determination and pharmacokinetic study of catechin in rat plasma by HPLC
por: Xie, Li, et al.
Publicado: (2011)

A Highly Sensitive Nonextraction-Assisted HPLC Method with Fluorescence Detection for Quantification of Duvelisib in Plasma Samples and its Application to Pharmacokinetic Study in Rats
por: Sayed, Ahmed Y, et al.
Publicado: (2021)

Cross-species comparison in nonclinical pharmacokinetics of lenvatinib by a simple HPLC with ultraviolet detection
por: Mizuo, Hitoshi, et al.
Publicado: (2023)

Simple HPLC-UV Method for Piperacillin/Tazobactam Assay in Human Plasma
por: Abdelkawy, Khaled, et al.
Publicado: (2023)

Pharmacokinetic Analysis of Zonarol, a Marine Algal Hydroquinone, in Mice Using HPLC with Fluorescence Detection
por: Fei, Jiyao, et al.
Publicado: (2023)

Simultaneous quantitation of folic acid and 5-methyltetrahydrofolic acid in human plasma by HPLC–MS/MS and its application to a pharmacokinetic study()
por: Zheng, Xiao-Hong, et al.
Publicado: (2015)

A Simple RP-HPLC Method for Quantitation of Itopride HCl in Tablet Dosage Form
por: Thiruvengada, Rajan VS, et al.
Publicado: (2010)

Determination of fenticonazole in human plasma by HPLC–MS/MS and its application to pharmacokinetic studies()
por: Mao, Weixing, et al.
Publicado: (2017)

Determination of Puquitinib in Human Plasma by HPLC–ESI MS/MS: Application to Pharmacokinetic Study
por: Zhan, Jing, et al.
Publicado: (2018)

Validated HPLC method for quantification of copanlisib in mice plasma: application to a pharmacokinetic study
por: Zakkula, Ashok, et al.
Publicado: (2020)

Evaluation of Cyclosporine Pharmacokinetic, Monitoring, and Dosing Parameters for GVHD Prophylaxis in Hematopoietic Stem Cell Transplant (HSCT) Recipients
por: Tafazoli, Ali, et al.
Publicado: (2019)

Simple, Precise and Accurate HPLC Method of Analysis for Nevirapine Suspension from Human Plasma
por: Halde, S., et al.
Publicado: (2011)

A Simple Sample Preparation with HPLC-UV Method for Estimation of Clomipramine from Plasma
por: Mostafavi, Sayed Abolfazl, et al.
Publicado: (2010)

Development and validation of a HPLC-MS/MS method with electrospray ionization for quantitation of potassium oxonate in human plasma: Application to a pharmacokinetic study
por: HAO, GUANGTAO, et al.
Publicado: (2013)

Quantitative HPLC-MS/MS determination of Nuc, the active metabolite of remdesivir, and its pharmacokinetics in rat
por: Du, Ping, et al.
Publicado: (2021)

A Rapid and Sensitive HPLC-Fluorescence Method for Determination of Mirtazapine and Its two Major Metabolites in Human Plasma
por: Lavasani, Hoda, et al.
Publicado: (2014)

Physiologically Based Pharmacokinetic Modelling and Simulation to Predict the Plasma Concentration Profile of Doxorubicin
por: Mystridis, George A., et al.
Publicado: (2022)

Plasma Pharmacokinetics and Tissue Distribution of Doxorubicin in Rats following Treatment with Astragali Radix
por: Huang, Yin, et al.
Publicado: (2022)

A simple method for quantitating confocal fluorescent images
por: Shihan, Mahbubul H., et al.
Publicado: (2021)

Validated HPLC-UV Method for Simultaneous Estimation of Paclitaxel and Doxorubicin Employing Ion Pair Chromatography: Application in Formulation Development and Pharmacokinetic Studies
por: Saklani, Ravi, et al.
Publicado: (2022)

An Interfering Substance in Gel Tubes Affects Vitamin D Measurement by HPLC
por: Haeri, Mohammad Reza, et al.
Publicado: (2023)

Determination of venlafaxine and its active metabolite O-desmethylvenlafaxine in human plasma by HPLC fluorescence
por: Shen, Shujuan, et al.
Publicado: (2018)

Cucurbituril—assisted sensitive fluorescence detection and quantitation of naproxen drug in wastewater samples: Guest-host characterization and HPLC investigation
por: Meetani, Mohammed A., et al.
Publicado: (2022)

Development and Validation of a HPLC Method to Determine Griseofulvin in Rat Plasma: Application to Pharmacokinetic Studies
por: Wei, Bo, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_0venn4rjgfr38fhr30prbd6g4v