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Antinociceptive Effects of Transcytosed Botulinum Neurotoxin Type A on Trigeminal Nociception in Rats

We examined the effects of peripherally or centrally administered botulinum neurotoxin type A (BoNT-A) on orofacial inflammatory pain to evaluate the antinociceptive effect of BoNT-A and its underlying mechanisms. The experiments were carried out on male Sprague-Dawley rats. Subcutaneous (3 U/kg) or...

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Detalles Bibliográficos
Autores principales: Kim, Hye-Jin, Lee, Geun-Woo, Kim, Min-Ji, Yang, Kui-Ye, Kim, Seong-Taek, Bae, Yong-Cheol, Ahn, Dong-Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499647/
https://www.ncbi.nlm.nih.gov/pubmed/26170739
http://dx.doi.org/10.4196/kjpp.2015.19.4.349