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Force-induced remodelling of proteins and their complexes

Force can drive conformational changes in proteins, as well as modulate their stability and the affinity of their complexes, allowing a mechanical input to be converted into a biochemical output. These properties have been utilised by nature and force is now recognised to be widely used at the cellu...

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Detalles Bibliográficos
Autores principales: Chen, Yun, Radford, Sheena E, Brockwell, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499843/
https://www.ncbi.nlm.nih.gov/pubmed/25710390
http://dx.doi.org/10.1016/j.sbi.2015.02.001