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The colibactin warhead crosslinks DNA

Members of the human microbiota are increasingly being correlated to human health and disease states, but the majority of the underlying microbial metabolites that regulate host-microbe interactions remain largely unexplored. Select strains of E. coli present in the human colon have been linked to i...

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Detalles Bibliográficos
Autores principales: Vizcaino, Maria I., Crawford, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499846/
https://www.ncbi.nlm.nih.gov/pubmed/25901819
http://dx.doi.org/10.1038/nchem.2221