PTEN Regulates DNA Replication Progression and Stalled Fork Recovery

Faithful DNA replication is a cornerstone of genomic integrity. PTEN plays multiple roles in genome protection and tumor suppression. Here we report on the importance of PTEN in DNA replication. PTEN depletion leads to impairment of replication progression and stalled fork recovery, indicating an el...

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Detalles Bibliográficos
Autores principales: He, Jinxue, Kang, Xi, Yin, Yuxin, Chao, K.S. Clifford, Shen, Wen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499867/
https://www.ncbi.nlm.nih.gov/pubmed/26158445
http://dx.doi.org/10.1038/ncomms8620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499867/
https://www.ncbi.nlm.nih.gov/pubmed/26158445
http://dx.doi.org/10.1038/ncomms8620

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