Cargando…

PTEN Regulates DNA Replication Progression and Stalled Fork Recovery

Faithful DNA replication is a cornerstone of genomic integrity. PTEN plays multiple roles in genome protection and tumor suppression. Here we report on the importance of PTEN in DNA replication. PTEN depletion leads to impairment of replication progression and stalled fork recovery, indicating an el...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Jinxue, Kang, Xi, Yin, Yuxin, Chao, K.S. Clifford, Shen, Wen H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499867/ https://www.ncbi.nlm.nih.gov/pubmed/26158445 http://dx.doi.org/10.1038/ncomms8620

Ejemplares similares

Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery
por: Murphy, Anar K., et al.
Publicado: (2014)

Advances in understanding DNA processing and protection at stalled replication forks
por: Rickman, Kimberly, et al.
Publicado: (2019)

BLM SUMOylation regulates ssDNA accumulation at stalled replication forks
por: Ouyang, Karen J., et al.
Publicado: (2013)

Forks on the Run: Can the Stalling of DNA Replication Promote Epigenetic Changes?
por: Rowlands, Hollie, et al.
Publicado: (2017)

PHOSPHORYLATION-DEPENDENT ASSOCIATION OF WRN WITH RPA IS REQUIRED FOR RECOVERY OF REPLICATION FORKS STALLED AT SECONDARY DNA STRUCTURES
por: Noto, Alessandro, et al.
Publicado: (2023)

Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA
por: Iyer, Divya Ramalingam, et al.
Publicado: (2017)

A stalled fork stalls recombination
por: Tuma, Rabiya S.
Publicado: (2005)

A model of DNA damage response activation at stalled replication forks by SPRTN
por: Bruhn, Christopher, et al.
Publicado: (2019)

Super-resolution visualization of distinct stalled and broken replication fork structures
por: Whelan, Donna R., et al.
Publicado: (2020)

Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks
por: George, Tresa, et al.
Publicado: (2009)

A protective role for BRCA2 at stalled replication forks
por: Chandramouly, Gurushankar, et al.
Publicado: (2011)

Metnase promotes restart and repair of stalled and collapsed replication forks
por: De Haro, Leyma P., et al.
Publicado: (2010)

Role of SUMO modification of human PCNA at stalled replication fork
por: Gali, Himabindu, et al.
Publicado: (2012)

Stalled replication forks within heterochromatin require ATRX for protection
por: Huh, M S, et al.
Publicado: (2016)

DNA polymerase IV mediates efficient and quick recovery of replication forks stalled at N(2)-dG adducts
por: Ikeda, Mio, et al.
Publicado: (2014)

Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulation
por: Minca, Eugen C., et al.
Publicado: (2011)

A fork in the road: Where homologous recombination and stalled replication fork protection part ways
por: Tye, Stephanie, et al.
Publicado: (2021)

UV stalled replication forks restart by re-priming in human fibroblasts
por: Elvers, Ingegerd, et al.
Publicado: (2011)

Continued primer synthesis at stalled replication forks contributes to checkpoint activation
por: Van, Christopher, et al.
Publicado: (2010)

Non-enzymatic roles of human RAD51 at stalled replication forks
por: Mason, Jennifer M., et al.
Publicado: (2019)

Single-molecule insight into stalled replication fork rescue in Escherichia coli
por: Bianco, Piero R, et al.
Publicado: (2021)

Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I–DNA complexes
por: Regairaz, Marie, et al.
Publicado: (2011)

DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation
por: Bétous, Rémy, et al.
Publicado: (2013)

DNA Helicase-SSB Interactions Critical to the Regression and Restart of Stalled DNA Replication Forks in Escherichia coli
por: Bianco, Piero R.
Publicado: (2020)

The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks
por: Shorrocks, Ann-Marie K., et al.
Publicado: (2021)

Ectopic RNF168 expression promotes break-induced replication-like DNA synthesis at stalled replication forks
por: Krais, John J, et al.
Publicado: (2020)

Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
por: Somyajit, Kumar, et al.
Publicado: (2015)

Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue
por: Appanah, Rowin, et al.
Publicado: (2020)

Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
por: Somyajit, Kumar, et al.
Publicado: (2020)

The mechanism of replication stalling and recovery within repetitive DNA
por: Casas-Delucchi, Corella S., et al.
Publicado: (2022)

Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stability
por: Graziano, Simona, et al.
Publicado: (2021)

RecG and UvsW catalyse robust DNA rewinding critical for stalled DNA replication fork rescue
por: Manosas, Maria, et al.
Publicado: (2013)

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
por: Pomerantz, Richard T., et al.
Publicado: (2010)

RecG interacts directly with SSB: implications for stalled replication fork regression
por: Buss, Jackson A., et al.
Publicado: (2008)

The abundance of Fob1 modulates the efficiency of rRFBs to stall replication forks
por: Castán, Alicia, et al.
Publicado: (2017)

Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks
por: Chaudhury, Indrajit, et al.
Publicado: (2017)

SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks
por: Rageul, Julie, et al.
Publicado: (2020)

DisA Limits RecG Activities at Stalled or Reversed Replication Forks
por: Torres, Rubén, et al.
Publicado: (2021)

Cohesin-dependent chromosome loop extrusion is limited by transcription and stalled replication forks
por: Jeppsson, Kristian, et al.
Publicado: (2022)

A fresh start for stalled forks
por: Leslie, Mitch
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_s0klj8c643b0houcb3alfjrkm2