Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ

Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation. The underlying molecular mechanisms, however, remain poorly understood,...

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Detalles Bibliográficos
Autores principales: Thi-Kim Vu, Hanh, Rink, Jochen C, McKinney, Sean A, McClain, Melainia, Lakshmanaperumal, Naharajan, Alexander, Richard, Sánchez Alvarado, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500094/
https://www.ncbi.nlm.nih.gov/pubmed/26057828
http://dx.doi.org/10.7554/eLife.07405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500094/
https://www.ncbi.nlm.nih.gov/pubmed/26057828
http://dx.doi.org/10.7554/eLife.07405

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