CCHamide-2 Is an Orexigenic Brain-Gut Peptide in Drosophila

The neuroendocrine peptides CCHamide-1 and -2, encoded by the genes ccha1 and -2, are produced by endocrine cells in the midgut and by neurons in the brain of Drosophila melanogaster. Here, we used the CRISPR/Cas9 technique to disrupt the ccha1 and -2 genes and identify mutant phenotypes with a focu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Guilin R., Hauser, Frank, Rewitz, Kim F., Kondo, Shu, Engelbrecht, Alexander F., Didriksen, Anders K., Schjøtt, Suzanne R., Sembach, Frederikke E., Li, Shizhong, Søgaard, Karen C., Søndergaard, Leif, Grimmelikhuijzen, Cornelis J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500396/
https://www.ncbi.nlm.nih.gov/pubmed/26168160
http://dx.doi.org/10.1371/journal.pone.0133017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500396/
https://www.ncbi.nlm.nih.gov/pubmed/26168160
http://dx.doi.org/10.1371/journal.pone.0133017

Ejemplares similares