Computational Modeling of a Transcriptional Switch Underlying B-Lymphocyte Lineage Commitment of Hematopoietic Multipotent Cells

Despite progresses in identifying the cellular mechanisms at the basis of the differentiation of hematopoietic stem/progenitor cells, little is known about the regulatory circuitry at the basis of lineage commitment of hematopoietic multipotent progenitors. To address this issue, we propose a comput...

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Detalles Bibliográficos
Autores principales: Salerno, Luca, Cosentino, Carlo, Morrone, Giovanni, Amato, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500571/
https://www.ncbi.nlm.nih.gov/pubmed/26167861
http://dx.doi.org/10.1371/journal.pone.0132208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500571/
https://www.ncbi.nlm.nih.gov/pubmed/26167861
http://dx.doi.org/10.1371/journal.pone.0132208

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