Inhibition of myeloid differentiation factor 88 signaling mediated by histidine-grafted poly(β-amino ester) ester nanovector induces donor-specific liver allograft tolerance

Toll-like receptors (TLRs) activate biochemical pathways that evoke activation of innate immunity, which leads to dendritic cell maturation and initiation of adaptive immune responses that provoke allograft rejection. We aimed to prolong allograft survival by selectively inhibiting expression of mye...

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Detalles Bibliográficos
Autores principales: Hu, Fanguo, Wang, Hanjie, Zhang, Shuangnan, Peng, Yao, Su, Lin, Chang, Jin, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500616/
https://www.ncbi.nlm.nih.gov/pubmed/26185440
http://dx.doi.org/10.2147/IJN.S81413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500616/
https://www.ncbi.nlm.nih.gov/pubmed/26185440
http://dx.doi.org/10.2147/IJN.S81413

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