Protective genotypes in HIV infection reflect superior function of KIR3DS1(+) over KIR3DL1(+) CD8(+) T cells

Certain human class I histocompatibility-linked leukocyte antigen (HLA)/killer cell immunoglobulin-like receptor (KIR) genotypic combinations confer more favourable prognoses upon exposure to human immunodeficiency virus (HIV). These combinations influence natural killer (NK) cell function, thereby...

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Detalles Bibliográficos
Autores principales: Zipperlen, Katrin, Gallant, Maureen, Stapleton, Staci, Heath, John, Barrett, Lisa, Grant, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500641/
https://www.ncbi.nlm.nih.gov/pubmed/25112829
http://dx.doi.org/10.1038/icb.2014.68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500641/
https://www.ncbi.nlm.nih.gov/pubmed/25112829
http://dx.doi.org/10.1038/icb.2014.68

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