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Protective genotypes in HIV infection reflect superior function of KIR3DS1(+) over KIR3DL1(+) CD8(+) T cells
Certain human class I histocompatibility-linked leukocyte antigen (HLA)/killer cell immunoglobulin-like receptor (KIR) genotypic combinations confer more favourable prognoses upon exposure to human immunodeficiency virus (HIV). These combinations influence natural killer (NK) cell function, thereby...
Autores principales: | Zipperlen, Katrin, Gallant, Maureen, Stapleton, Staci, Heath, John, Barrett, Lisa, Grant, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500641/ https://www.ncbi.nlm.nih.gov/pubmed/25112829 http://dx.doi.org/10.1038/icb.2014.68 |
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