Mucin 1 Regulates Cox-2 Gene in Pancreatic Cancer

OBJECTIVE: Eighty percent of pancreatic ductal adenocarcinomas (PDAs) overexpress mucin 1 (MUC1), a transmembrane mucin glycoprotein. MUC1(high) PDA patients also express high levels of cyclooxygenase 2 (COX-2) and show poor prognosis. The cytoplasmic tail of MUC1 (MUC1-CT) partakes in oncogenic sig...

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Detalles Bibliográficos
Autores principales: Nath, Sritama, Roy, Lopamudra Das, Grover, Priyanka, Rao, Shanti, Mukherjee, Pinku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500655/
https://www.ncbi.nlm.nih.gov/pubmed/26035123
http://dx.doi.org/10.1097/MPA.0000000000000371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500655/
https://www.ncbi.nlm.nih.gov/pubmed/26035123
http://dx.doi.org/10.1097/MPA.0000000000000371

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