Frog intestinal perfusion to evaluate drug permeability: application to p-gp and cyp3a4 substrates

To evaluate the reliability of using in situ frog intestinal perfusion technique for permeability assessment of carrier transported drugs which are also substrates for CYP enzymes. Single Pass Intestinal Perfusion (SPIP) studies were performed in frogs of the species Rana tigrina using established m...

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Detalles Bibliográficos
Autores principales: Yerasi, Neelima, Vurimindi, Himabindu, Devarakonda, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500896/
https://www.ncbi.nlm.nih.gov/pubmed/26236236
http://dx.doi.org/10.3389/fphar.2015.00141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500896/
https://www.ncbi.nlm.nih.gov/pubmed/26236236
http://dx.doi.org/10.3389/fphar.2015.00141

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