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Analysis of mixtures using next generation sequencing of mitochondrial DNA hypervariable regions

AIM: To apply massively parallel and clonal sequencing (next generation sequencing or NGS) to the analysis of forensic mixed samples. METHODS: A duplex polymerase chain reaction (PCR) assay targeting the mitochondrial DNA (mtDNA) hypervariable regions I/II (HVI/HVII) was developed for NGS analysis o...

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Detalles Bibliográficos
Autores principales: Kim, Hanna, Erlich, Henry A., Calloway, Cassandra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500979/
https://www.ncbi.nlm.nih.gov/pubmed/26088845
http://dx.doi.org/10.3325/cmj.2015.56.208