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HIV inhibits endothelial reverse cholesterol transport through impacting subcellular Caveolin-1 trafficking

BACKGROUND: Human immunodeficiency virus (HIV) infection leads to decreased reverse cholesterol transport (RCT) in macrophages, and Nef mediated down-regulation and redistribution of ATP-binding cassette transporter A1 (ABCA1) are identified as key factors for this effect. This may partially explain...

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Detalles Bibliográficos
Autores principales: Lin, Shanshan, Nadeau, Peter E, Mergia, Ayalew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501058/
https://www.ncbi.nlm.nih.gov/pubmed/26169283
http://dx.doi.org/10.1186/s12977-015-0188-y