Cargando…
Fast imputation using medium or low-coverage sequence data
BACKGROUND: Accurate genotype imputation can greatly reduce costs and increase benefits by combining whole-genome sequence data of varying read depth and array genotypes of varying densities. For large populations, an efficient strategy chooses the two haplotypes most likely to form each genotype an...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501077/ https://www.ncbi.nlm.nih.gov/pubmed/26168789 http://dx.doi.org/10.1186/s12863-015-0243-7 |