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Fast imputation using medium or low-coverage sequence data
BACKGROUND: Accurate genotype imputation can greatly reduce costs and increase benefits by combining whole-genome sequence data of varying read depth and array genotypes of varying densities. For large populations, an efficient strategy chooses the two haplotypes most likely to form each genotype an...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501077/ https://www.ncbi.nlm.nih.gov/pubmed/26168789 http://dx.doi.org/10.1186/s12863-015-0243-7 |