The role of climate and out-of-Africa migration in the frequencies of risk alleles for 21 human diseases

BACKGROUND: Demography and environmental adaptation can affect the global distribution of genetic variants and possibly the distribution of disease. Population heterozygosity of single nucleotide polymorphisms has been shown to decrease strongly with distance from Africa and this has been attributed...

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Detalles Bibliográficos
Autores principales: Blair, Lily M., Feldman, Marcus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501093/
https://www.ncbi.nlm.nih.gov/pubmed/26170196
http://dx.doi.org/10.1186/s12863-015-0239-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501093/
https://www.ncbi.nlm.nih.gov/pubmed/26170196
http://dx.doi.org/10.1186/s12863-015-0239-3

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