Fast and scalable inference of multi-sample cancer lineages

Somatic variants can be used as lineage markers for the phylogenetic reconstruction of cancer evolution. Since somatic phylogenetics is complicated by sample heterogeneity, novel specialized tree-building methods are required for cancer phylogeny reconstruction. We present LICHeE (Lineage Inference...

Descripción completa

Detalles Bibliográficos
Autores principales: Popic, Victoria, Salari, Raheleh, Hajirasouliha, Iman, Kashef-Haghighi, Dorna, West, Robert B, Batzoglou, Serafim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501097/
https://www.ncbi.nlm.nih.gov/pubmed/25944252
http://dx.doi.org/10.1186/s13059-015-0647-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501097/
https://www.ncbi.nlm.nih.gov/pubmed/25944252
http://dx.doi.org/10.1186/s13059-015-0647-8

Ejemplares similares