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Fast and scalable inference of multi-sample cancer lineages

Somatic variants can be used as lineage markers for the phylogenetic reconstruction of cancer evolution. Since somatic phylogenetics is complicated by sample heterogeneity, novel specialized tree-building methods are required for cancer phylogeny reconstruction. We present LICHeE (Lineage Inference...

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Detalles Bibliográficos
Autores principales:	Popic, Victoria, Salari, Raheleh, Hajirasouliha, Iman, Kashef-Haghighi, Dorna, West, Robert B, Batzoglou, Serafim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501097/ https://www.ncbi.nlm.nih.gov/pubmed/25944252 http://dx.doi.org/10.1186/s13059-015-0647-8

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