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Monitoring PfMDR1 transport in Plasmodium falciparum

BACKGROUND: The Plasmodium falciparum multidrug resistance 1 transporter, PfMDR1, contains five amino acid polymorphisms that are suggested to be involved in altered drug transport from the parasite’s cytosol into the digestive vacuole (DV). Transport of a substrate into another intracellular compar...

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Detalles Bibliográficos
Autores principales: Reiling, Sarah J, Rohrbach, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501111/
https://www.ncbi.nlm.nih.gov/pubmed/26169590
http://dx.doi.org/10.1186/s12936-015-0791-3