Stem cell models of polyglutamine diseases and their use in cell-based therapies

Polyglutamine diseases are fatal neurological disorders that affect the central nervous system. They are caused by mutations in disease genes that contain CAG trinucleotide expansions in their coding regions. These mutations are translated into expanded glutamine chains in pathological proteins. Mut...

Descripción completa

Detalles Bibliográficos
Autores principales: Siska, Evangelia K., Koliakos, George, Petrakis, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501170/
https://www.ncbi.nlm.nih.gov/pubmed/26236184
http://dx.doi.org/10.3389/fnins.2015.00247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501170/
https://www.ncbi.nlm.nih.gov/pubmed/26236184
http://dx.doi.org/10.3389/fnins.2015.00247

Ejemplares similares