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In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses

BACKGROUND: Rhinovirus infections do not only cause common colds, but may also trigger severe exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Even though rhinoviruses have been the focus of extensive drug development efforts in the past, an anti-rhinoviral drug still has to...

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Detalles Bibliográficos
Autores principales: Lacroix, Céline, Laconi, Samuela, Angius, Fabrizio, Coluccia, Antonio, Silvestri, Romano, Pompei, Raffaello, Neyts, Johan, Leyssen, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501209/
https://www.ncbi.nlm.nih.gov/pubmed/26169596
http://dx.doi.org/10.1186/s12985-015-0330-4