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Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells

BACKGROUND: Human lung mast cells (HLMCs) infiltrate the airway epithelium and airway smooth muscle (ASM) in asthmatic airways. The mechanism of HLMC adhesion to both cell types is only partly defined, and adhesion is not inhibited by function-blocking anti-Kit and anti-stem cell factor (SCF) antibo...

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Detalles Bibliográficos
Autores principales: Gough, Kevin C., Maddison, Ben C., Shikotra, Aarti, Moiseeva, Elena P., Yang, Weidong, Jarvis, Shila, Bradding, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501212/
https://www.ncbi.nlm.nih.gov/pubmed/26173671
http://dx.doi.org/10.1186/s12931-015-0245-z