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Glanzmann’s thrombasthenia: pathogenesis, diagnosis, and current and emerging treatment options
Glanzmann’s thrombasthenia (GT) is a genetic platelet surface receptor disorder of GPIIb/IIIa (ITG αIIbβ3), either qualitative or quantitative, which results in faulty platelet aggregation and diminished clot retraction. Spontaneous mucocutaneous bleeding is common and can lead to fatal bleeding epi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501245/ https://www.ncbi.nlm.nih.gov/pubmed/26185478 http://dx.doi.org/10.2147/JBM.S71319 |