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Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment

We observed the dynamic recruitment of spindle checkpoint proteins Mad1 and Bub1 to detached kinetochores in budding yeast using real-time live-cell imaging and quantified recruitment in fixed cells. After induced de novo kinetochore assembly at one pair of sister centromeres, Mad1 appeared after th...

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Detalles Bibliográficos
Autores principales: Krefman, Nathaniel I., Drubin, David G., Barnes, Georjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501360/
https://www.ncbi.nlm.nih.gov/pubmed/26023090
http://dx.doi.org/10.1091/mbc.E15-05-0276