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A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes

Assembly of a bipolar microtubule spindle is essential for accurate chromosome segregation. In somatic cells, spindle bipolarity is determined by the presence of exactly two centrosomes. Remarkably, mammalian oocytes do not contain canonical centrosomes. This study reveals that mouse oocytes assembl...

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Detalles Bibliográficos
Autores principales:	Clift, Dean, Schuh, Melina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501430/ https://www.ncbi.nlm.nih.gov/pubmed/26147444 http://dx.doi.org/10.1038/ncomms8217

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