Cargando…

The core spliceosome as target and effector of non-canonical ATM signaling

In response to DNA damage tissue homoeostasis is ensured by protein networks promoting DNA repair, cell cycle arrest or apoptosis. DNA damage response signaling pathways coordinate these processes, partly by propagating gene expression-modulating signals. DNA damage influences not only abundance of...

Descripción completa

Detalles Bibliográficos
Autores principales: Tresini, Maria, Warmerdam, Daniël O., Kolovos, Petros, Snijder, Loes, Vrouwe, Mischa G., Demmers, Jeroen A.A., van IJcken, Wilfred F.J., Grosveld, Frank G., Medema, René H., Hoeijmakers, Jan H.J., Mullenders, Leon H.F., Vermeulen, Wim, Marteijn, Jurgen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501432/
https://www.ncbi.nlm.nih.gov/pubmed/26106861
http://dx.doi.org/10.1038/nature14512