Temporal trends in prevalence of Plasmodium falciparum molecular markers selected for by artemether–lumefantrine treatment in pre-ACT and post-ACT parasites in western Kenya

Artemether–lumefantrine (AL) became the first-line treatment for uncomplicated malaria in Kenya in 2006. Studies have shown AL selects for SNPs in pfcrt and pfmdr1 genes in recurring parasites compared to the baseline infections. The genotypes associated with AL selection are K76 in pfcrt and N86, 1...

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Detalles Bibliográficos
Autores principales: Achieng, Angela O., Muiruri, Peninah, Ingasia, Luicer A., Opot, Benjamin H., Juma, Dennis W., Yeda, Redemptah, Ngalah, Bidii S., Ogutu, Bernhards R., Andagalu, Ben, Akala, Hoseah M., Kamau, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501530/
https://www.ncbi.nlm.nih.gov/pubmed/26236581
http://dx.doi.org/10.1016/j.ijpddr.2015.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501530/
https://www.ncbi.nlm.nih.gov/pubmed/26236581
http://dx.doi.org/10.1016/j.ijpddr.2015.05.005

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