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Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) constitute a major source of type-I interferon (IFN-I) production during acute HIV infection. Their activation results primarily from TLR7-mediated sensing of HIV-infected cells. However, the interactions between HIV-infected T cells and pDCs that modulate this se...

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Detalles Bibliográficos
Autores principales: Bego, Mariana G., Côté, Édouard, Aschman, Nick, Mercier, Johanne, Weissenhorn, Winfried, Cohen, Éric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501562/
https://www.ncbi.nlm.nih.gov/pubmed/26172439
http://dx.doi.org/10.1371/journal.ppat.1005024