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BCL2 Inhibitor (ABT-737): A Restorer of Prednisolone Sensitivity in Early T-Cell Precursor-Acute Lymphoblastic Leukemia with High MEF2C Expression?

Early T-cell precursor-acute lymphoblastic leukemia (ETP-ALL) has been identified as a high-risk subtype of pediatric T-cell acute lymphoblastic leukemia (T-ALL). Conventional chemotherapy is not fully effective for this subtype of leukemia; therefore, potential therapeutic targets need to be explor...

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Detalles Bibliográficos
Autores principales: Kawashima-Goto, Sachiko, Imamura, Toshihiko, Tomoyasu, Chihiro, Yano, Mio, Yoshida, Hideki, Fujiki, Atsushi, Tamura, Shinichi, Osone, Shinya, Ishida, Hiroyuki, Morimoto, Akira, Kuroda, Hiroshi, Hosoi, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501565/
https://www.ncbi.nlm.nih.gov/pubmed/26172269
http://dx.doi.org/10.1371/journal.pone.0132926