The Schizophrenia-Related Protein Dysbindin-1A Is Degraded and Facilitates NF-Kappa B Activity in the Nucleus

Dystrobrevin-binding protein 1 (DTNBP1), a gene encoding dysbindin-1, has been identified as a susceptibility gene for schizophrenia. Functioning with partners in synapses or the cytoplasm, this gene regulates neurite outgrowth and neurotransmitter release. Loss of dysbindin-1 affects schizophrenia...

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Detalles Bibliográficos
Autores principales: Fu, Cheng, Chen, Dong, Chen, Ruijie, Hu, Qingsong, Wang, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501731/
https://www.ncbi.nlm.nih.gov/pubmed/26171858
http://dx.doi.org/10.1371/journal.pone.0132639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501731/
https://www.ncbi.nlm.nih.gov/pubmed/26171858
http://dx.doi.org/10.1371/journal.pone.0132639

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