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Normal Platelet Integrin Function in Mice Lacking Hydrogen Peroxide-Induced Clone-5 (Hic-5)

Integrin αIIbβ3 plays a central role in the adhesion and aggregation of platelets and thus is essential for hemostasis and thrombosis. Integrin activation requires the transmission of a signal from the small cytoplasmic tails of the α or β subunit to the large extracellular domains resulting in conf...

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Detalles Bibliográficos
Autores principales: Popp, Michael, Thielmann, Ina, Nieswandt, Bernhard, Stegner, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501753/
https://www.ncbi.nlm.nih.gov/pubmed/26172113
http://dx.doi.org/10.1371/journal.pone.0133429