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The Intracellular Localisation and Phosphorylation Profile of the Human 5-Lipoxygenase Δ13 Isoform Differs from That of Its Full Length Counterpart

5-Lipoxygenase (5-LO) catalyzes leukotriene (LT) biosynthesis by a mechanism that involves interactions with 5-lipoxygenase activating protein (FLAP) and coactosin-like protein (CLP). 5-LO splice variants were recently identified in human myeloid and lymphoid cells, including the catalytically inact...

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Detalles Bibliográficos
Autores principales: Allain, Eric P., Boudreau, Luc H., Flamand, Nicolas, Surette, Marc E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501781/
https://www.ncbi.nlm.nih.gov/pubmed/26173130
http://dx.doi.org/10.1371/journal.pone.0132607