Sample Size Calculation: Inaccurate A Priori Assumptions for Nuisance Parameters Can Greatly Affect the Power of a Randomized Controlled Trial

We aimed to examine the extent to which inaccurate assumptions for nuisance parameters used to calculate sample size can affect the power of a randomized controlled trial (RCT). In a simulation study, we separately considered an RCT with continuous, dichotomous or time-to-event outcomes, with associ...

Descripción completa

Detalles Bibliográficos
Autores principales: Tavernier, Elsa, Giraudeau, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501786/
https://www.ncbi.nlm.nih.gov/pubmed/26173007
http://dx.doi.org/10.1371/journal.pone.0132578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501786/
https://www.ncbi.nlm.nih.gov/pubmed/26173007
http://dx.doi.org/10.1371/journal.pone.0132578

Ejemplares similares