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MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del

We are using induced pluripotent stem cell (iPSC) technology to study neuropsychiatric disorders associated with 22q11.2 microdeletions (del), the most common known schizophrenia (SZ)-associated genetic factor. Several genes in the region have been implicated; a promising candidate is DGCR8, which c...

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Detalles Bibliográficos
Autores principales: Zhao, Dejian, Lin, Mingyan, Chen, Jian, Pedrosa, Erika, Hrabovsky, Anastasia, Fourcade, H. Matthew, Zheng, Deyou, Lachman, Herbert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501820/
https://www.ncbi.nlm.nih.gov/pubmed/26173148
http://dx.doi.org/10.1371/journal.pone.0132387