Cargando…

Single-cell polyadenylation site mapping reveals 3′ isoform choice variability

Cell-to-cell variability in gene expression is important for many processes in biology, including embryonic development and stem cell homeostasis. While heterogeneity of gene expression levels has been extensively studied, less attention has been paid to mRNA polyadenylation isoform choice. 3′ untra...

Descripción completa

Detalles Bibliográficos
Autores principales: Velten, Lars, Anders, Simon, Pekowska, Aleksandra, Järvelin, Aino I, Huber, Wolfgang, Pelechano, Vicent, Steinmetz, Lars M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501847/
https://www.ncbi.nlm.nih.gov/pubmed/26040288
http://dx.doi.org/10.15252/msb.20156198