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Interleukin (IL)-21 promotes intestinal IgA response to microbiota

Commensal microbiota-specific Th17 cells are enriched in the intestines, which can convert into Tfh in Peyer’s patches, and are crucial for production of intestinal IgA against microbiota, however, the role of Th17 and Tfh cytokines in regulating the mucosal IgA response to enteric microbiota is sti...

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Detalles Bibliográficos
Autores principales: Cao, Anthony T., Yao, Suxia, Gong, Bin, Nurieva, Roza I., Elson, Charles O., Cong, Yingzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501922/
https://www.ncbi.nlm.nih.gov/pubmed/25586558
http://dx.doi.org/10.1038/mi.2014.134