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P-coumaric acid regulates exon 12 splicing of the ATP7B gene by modulating hnRNP A1 protein expressions

Background: Wilson’s disease (WD) is a genetic disorder involving the metabolism of copper. WD patients exhibit a wide range of disease phenotypes, including Kayser-Fleischer rings in the cornea, predominant progressive hepatic disease, neurological diseases, and/or psychiatric illnesses, among othe...

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Detalles Bibliográficos
Autores principales: Lin, Ying-Ju, Ho, Tsung-Jung, Lin, Ting-Hsu, Hsu, Wei-Yi, Huang, Shao-Mei, Liao, Chiu-Chu, Lai, Chih-Ho, Liu, Xiang, Tsang, Hsinyi, Lai, Chien-Chen, Tsai, Fuu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: China Medical University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502042/
https://www.ncbi.nlm.nih.gov/pubmed/26048696
http://dx.doi.org/10.7603/s40681-015-0010-0