The Endoplasmic Reticulum Stress Sensor Inositol-Requiring Enzyme 1α Augments Bacterial Killing through Sustained Oxidant Production

Bacterial infection can trigger cellular stress programs, such as the unfolded protein response (UPR), which occurs when misfolded proteins accumulate within the endoplasmic reticulum (ER). Here, we used the human pathogen methicillin-resistant Staphylococcus aureus (MRSA) as an infection model to p...

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Detalles Bibliográficos
Autores principales: Abuaita, Basel H., Burkholder, Kristin M., Boles, Blaise R., O’Riordan, Mary X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502229/
https://www.ncbi.nlm.nih.gov/pubmed/26173697
http://dx.doi.org/10.1128/mBio.00705-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502229/
https://www.ncbi.nlm.nih.gov/pubmed/26173697
http://dx.doi.org/10.1128/mBio.00705-15

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