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Melatonin Modulates Endoplasmic Reticulum Stress and Akt/GSK3-Beta Signaling Pathway in a Rat Model of Renal Warm Ischemia Reperfusion

Melatonin (Mel) is widely used to attenuate ischemia/reperfusion (I/R) injury in several organs. Nevertheless, the underlying mechanisms remain unclear. This study was conducted to explore the effect of Mel on endoplasmic reticulum (ER) stress, Akt and MAPK cascades after renal warm I/R. Eighteen Wi...

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Detalles Bibliográficos
Autores principales: Hadj Ayed Tka, Kaouther, Mahfoudh Boussaid, Asma, Zaouali, Mohamed Amine, Kammoun, Rym, Bejaoui, Mohamed, Ghoul Mazgar, Sonia, Rosello Catafau, Joan, Ben Abdennebi, Hassen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502281/
https://www.ncbi.nlm.nih.gov/pubmed/26229743
http://dx.doi.org/10.1155/2015/635172