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Activation-Inactivation Cycling of Rab35 and ARF6 Is Required for Phagocytosis of Zymosan in RAW264 Macrophages

Phagocytosis of zymosan by phagocytes is a widely used model of microbial recognition by the innate immune system. Live-cell imaging showed that fluorescent protein-fused Rab35 accumulated in the membranes of phagocytic cups and then dissociated from the membranes of newly formed phagosomes. By our...

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Detalles Bibliográficos
Autores principales: Egami, Youhei, Fujii, Makoto, Kawai, Katsuhisa, Ishikawa, Yurie, Fukuda, Mitsunori, Araki, Nobukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502309/
https://www.ncbi.nlm.nih.gov/pubmed/26229970
http://dx.doi.org/10.1155/2015/429439