Differential connectivity of splicing activators and repressors to the human spliceosome

BACKGROUND: During spliceosome assembly, protein-protein interactions (PPI) are sequentially formed and disrupted to accommodate the spatial requirements of pre-mRNA substrate recognition and catalysis. Splicing activators and repressors, such as SR proteins and hnRNPs, modulate spliceosome assembly...

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Detalles Bibliográficos
Autores principales: Akerman, Martin, Fregoso, Oliver I., Das, Shipra, Ruse, Cristian, Jensen, Mads A., Pappin, Darryl J., Zhang, Michael Q., Krainer, Adrian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502471/
https://www.ncbi.nlm.nih.gov/pubmed/26047612
http://dx.doi.org/10.1186/s13059-015-0682-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502471/
https://www.ncbi.nlm.nih.gov/pubmed/26047612
http://dx.doi.org/10.1186/s13059-015-0682-5

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